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CGP EDU Academic Team
Published on: August 21, 2026
Which one of the following disorders is caused by the substitution of Glutamic acid (Glu) by Valine (Val) at the sixth position of the beta globin chain of the haemoglobin molecule?
Text Solution
Verified by ExpertsThe correct answer is:
C
Sickle-cell anaemia: Glutamic acid → Valine at 6 th position of 
-globin chain.
Phenylketonuria: Enzyme deficiency (Phenylalanine hydroxylase).
Haemophilia: Blood clotting defect.
Thalassemia: Quantitative defect (less globin produced).
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